General Information

  • ID:  hor003107
  • Uniprot ID:  A0A7M6UD51
  • Protein name:  Neuropeptide F
  • Gene name:  100313503
  • Organism:  Nasonia vitripennis (Parasitic wasp)
  • Family:  NPY family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Nasonia (genus), Pteromalinae (subfamily), Pteromalidae (family), Chalcidoidea (superfamily), Parasitoida (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005179 hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  EPEPMARPTRPKVFESPEELRQYLDLVKEYYSLSGKARY
  • Length:  39
  • Propeptide:  MRVSLAMMHLTYLTLTVLALGSVSVQSEPEPMARPTRPKVFESPEELRQYLDLVKEYYSLSGKARYGKRAEPYAMQQGYEHPLNFLRMLLAFSRQKQELVDKDERSKLQIMQPYDRVARYYEIME
  • Signal peptide:  MRVSLAMMHLTYLTLTVLALGSVSVQS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M6UD51-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003107_AF2.pdbhor003107_ESM.pdb

Physical Information

Mass: 535224 Formula: C211H327N55O63S
Absent amino acids: CHINW Common amino acids: E
pI: 6.74 Basic residues: 7
Polar residues: 9 Hydrophobic residues: 9
Hydrophobicity: -108.97 Boman Index: -10713
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 60
Instability Index: 6828.72 Extinction Coefficient cystines: 5960
Absorbance 280nm: 156.84

Literature

  • PubMed ID:  20695486
  • Title:  Genomics and Peptidomics of Neuropeptides and Protein Hormones Present in the Parasitic Wasp Nasonia Vitripennis